their interactions with target molecules in the body.These will enable rapid prediction and measurement of: Research could include use of these technologies to cut drug development costs and minimise the need for animal testing. In-silico, in-vitro and biomarker technologies for use in drug discovery optimisation of the capabilities of donated organs and tissues and maximisation of the benefits they deliver.creation of human organs in the lab – avoiding the need to rely on donors when damaged organs need replacement or repair.enable development of new materials to promote tissue growth.Research could include innovative technologies that will: Innovative technologies for regenerative medicine It could also include processes that will be capable of scale down to produce personalised medicines, such as regenerative therapies using patients’ own cells. Research could include processes that will be capable of cost-effective scale up to enable mass production of medicines – for example, to tackle epidemics. deliver more than one active ingredient at a time.įlexible, adaptable processes for manufacturing high-quality therapies.achieve controlled release of their active ingredients.Research could include but will not be limited to projects delivering these technologies to boost the effectiveness with which novel drugs and other pharmaceutical substances: Advanced technologies to enhance drug delivery This can not only cut time-to-market for new therapies but can also pinpoint opportunities for repurposing drugs to target additional diseases, maximising the benefits of investing in drug development. Research could include but will not be limited to projects delivering multiscale computer modelling, adaptive design and data analytics, for example. Advanced technologies ready for clinical trials There are several ways that research could do this. This challenge focuses on the need to produce safer, more targeted treatments fit for the demands of the decades up to 2050 and beyond.īy enabling earlier intervention, and more accurate, less invasive, more affordable action, these will not just prevent, slow or reverse deterioration in physical and mental health but also enhance quality of life by eliminating or alleviating symptoms. In a world challenged and changed by the COVID-19 pandemic, the unrelenting drive to tackle existing and emerging diseases by harnessing engineering and physical sciences to develop new therapies must continue apace. stimulating creative and transformational approaches to address unmet clinical needs and improve patient outcomes.ĭeveloping new therapies Flexible, adaptable processes for manufacturing high-quality therapies.providing support for environments that promote multidisciplinary research and training.partnerships with other funders to encourage translational research and open up pathways to impact.focusing on the highest priority healthcare challenges and the research capabilities that will address them.maximising business, charity and clinical engagement in research, thereby increasing translation to products and practices.building critical mass around UK research strengths in computational, engineering, mathematical and physical sciences that underpin healthcare.The vision of the healthcare technologies theme is to accelerate the translation of EPSRC research to healthcare applications by: optimising disease prediction, diagnosis and intervention: addressing both physical and mental health with techniques that optimise patient-specific illness prediction, accurate diagnosis and effective intervention.ĭiagram describing the healthcare technologies strategy.transforming health and care beyond the hospital: meeting the need for novel technologies that enable timely interventions beyond hospital settings and help people manage their own physical and mental health.expanding the frontiers of physical intervention: the potential to enhance established techniques and develop pioneering new approaches to such intervention that deliver high precision, minimal invasiveness and maximum impact.developing new therapies: focusing on the need to produce safer, more targeted treatments fit for the demands of the decades up to 2050 and beyond. In order to achieve this, we aim to address four grand challenges: The aim is to accelerate translation to healthcare applications. The healthcare technologies theme supports research across EPSRC’s remit.
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